Open Enzyme Team¶
Open Enzyme is a Phase 0 research and design project led by Brian Abent, with Lauren Collier Hyams, PhD, serving as Scientific Advisor.
Brian Abent — Founder¶
Brian leads Open Enzyme's research systems, platform design, engineering, and documentation. He brings a CTO and systems-engineering background to the project's central method: map gout as a system, identify exploitable weaknesses, and turn them into falsifiable research tracks.
Lauren Collier Hyams, PhD — Scientific Advisor¶
Lauren brings rare-disease medical affairs experience and a research background in innate immunity and intestinal epithelial biology. She reviews scientific claims and mechanistic interpretations, challenges hypotheses, and helps judge whether the evidence supports advancing, revising, or ending a research track.